OPSUMIT® (macitentan) efficacy
OPSUMIT® is a foundation for pulmonary arterial hypertension (PAH) treatment, and is recommended in first line as monotherapy as well as in combination therapy.[1][2] The efficacy of OPSUMIT® is demonstrated in the SERAPHIN, OPTIMA and REPAIR trials,[2][3][4][5] while the large real-world OPUS registry and OrPHeUS study show that OPSUMIT® is used effectively in a broad range of patients with PAH.[6][7][8][9][10]
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The OPTIMA trial explored the benefits of initial combination therapy with OPSUMIT® and tadalafil in patients with PAH.[4]
The REPAIR trial evaluated the effect of OPSUMIT® on right ventricular structure and function vs baseline.[5]
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PAH, pulmonary arterial hypertension
OPSUMIT® PRESCRIBING INFORMATION AND ADVERSE EVENT REPORTING
CP-220224 | June 2021
